reasoning benchmark
DNA sequence design for transcription factor binding evaluates whether models can design DNA sequences with high transcription-factor affinity relative to a Ledidi baseline on Nucleobench-derived prompts.
Updated Oct 23, 2026
Higher score ranks better on this benchmark.
Rank | Model | Score | Percentile | Participants | Evidence | Evaluated |
|---|
| Rank01 | ModelOP | Score13.64% | Percentile100.00% | Participants1 | EvidenceC | Evaluated |
The leading models and scores on this benchmark.
The first five results on this benchmark, with official price and output speed added where the model identity can be matched.
What DNA sequence design for transcription factor binding measures and how its scores work.
An OpenAI evaluation of DNA sequence design for transcription factor binding using Nucleobench-derived prompts and a Ledidi baseline.
It measures Score, reported as a ratio, for transcription-factor affinity relative to the Ledidi baseline.
Scores are shown in ratio. This benchmark is not independently verified and has an evidence level of B.
LLM Stats. Benchmark scores retain their original unit. Overall score eligibility is shown separately.
Common questions about DNA sequence design for transcription factor binding.
GPT-Rosalind is currently ranked first with 13.64%.
The current leaders are GPT-Rosalind (13.64%).
No matched official input price is currently available.
No matched runtime record is currently available.
No. This benchmark measures one defined capability or task. The overall LLMBoard score uses a separate aggregation across eligible benchmark evidence.
It measures Score, reported as a ratio, for transcription-factor affinity relative to the Ledidi baseline.
Yes. Higher values rank better for this benchmark.
1 model results are currently shown.
No. This benchmark is shown for reference but does not contribute to the overall score.
Ranking basisThis dna sequence design for transcription factor binding AI model leaderboard uses descending score in the benchmark original unit. The leaderboard ranking keeps matched price and speed data separate from benchmark evidence.
Selection summary
GPT-Rosalind currently leads DNA sequence design for transcription factor binding with 13.64%. It is the top model on this specific benchmark, while the best LLM for the broader task should also be checked against other benchmarks, price, and runtime.
Use this leaderboard with the supporting benchmark results and coverage details above. A leaderboard position summarizes the selected ranking signal; it does not replace workload-specific testing.